Sistema de Eventos Acadêmicos da UFMT, X Mostra da Pós-Graduação: Direitos Humanos, trabalho coletivo e redes de pesquisa na Pós Graduação

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ALTERAÇÕES LABORATORIAIS EM PACIENTES INFECTADOS COM MALÁRIA POR PLASMODIUM VIVAX PROCEDENTES DA AMAZÔNIA BRASILEIRA NO PERÍODO DE 2010 A 2016
Eduardo Rodrigues Alves Junior, Cor Jesus Fernandes Fontes, Fabrício Rios Santos

Última alteração: 05-10-18

Resumo


No Brasil, a maior parte dos casos de infecção malárica se concentra na região amazônica, sendo o Plasmodium vivax responsável por 90% dos casos. Após diagnóstico da infecção, para avaliar o prognóstico e evolução da doença, a equipe médica solicita parâmetros laboratoriais auxiliares. O objetivo do presente estudo foi comparar os resultados de 42 parâmetros laboratoriais entre o dia do diagnóstico (infecção aguda) e o dia do retorno para verificação de cura (convalescência). Trata-se de uma coorte aberta com 191 pacientes diagnosticados com P. vivax atendidos de 2010 a 2016 em um centro de referência de diagnóstico de malária em Cuiabá, Matogrosso. Dos 42 parâmetros laboratoriais avaliados, 32 apresentaram alterações com associação significativa com o quadro de infecção aguda quando comparados com o quadro de convalescência. São preconizados pela WHO nove parâmetros laboratoriais para identificação de malária grave, porém vários são os parâmetros que indicam o estado agudo da infecção por P. vivax que por ser uma doença inflamatória sistêmica apresenta um quadro laboratorial ainda não totalmente explorado.



Palavras-chave


Plasmodium vivax, parâmetros laboratoriais, biomarcadores, prognóstico

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